New guidelines for metformin and diabetes mellitus


Abstract: We review clinical evidence related to the use of metformin for treatment of type-2 diabetes mellitus and provide new clinical guideline recommendations.

MeSH subject headings: Metformin ; Diabetes Mellitus, Type 2

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Guidelines

Recommendation: we recommend monotherapy with metformin as an initial pharmacologic therapy to treat most patients with type 2 diabetes (Grade: strong recommendation; high-quality evidence).