New guidelines for metformin and diabetes mellitus

Abstract: We review clinical evidence related to the use of metformin for treatment of type-2 diabetes mellitus and provide new clinical guideline recommendations.

MeSH subject headings: Metformin ; Diabetes Mellitus, Type 2



Recommendation: we recommend monotherapy with metformin as an initial pharmacologic therapy to treat most patients with type 2 diabetes (Grade: strong recommendation; high-quality evidence).